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Mercedes-Benz S 320 CDI

OM642 3.0L V6 Diesel 235 hp Automatic Rear-wheel drive Sedan 2006–2013
βœ– Stay Away!
Engine OM642 βœ– Stay Away! 10,200–31,400 €

V6 diesel with common rail and piezo injectors. Powerful and refined. Known for blocked oil coolers, swirl flap failure and EGR problems. High mileages possible with good maintenance.

Fun Factor? Decent

Diesel Standard

173 kW diesel. Functional and economical, emotionless.

Engine Weaknesses 7

!! Oil Cooler Gaskets Leaking β€” Oil and Coolant Loss

The best-known problem of the OM642: the oil cooler gaskets in the V-section of the engine fail. Oil leaks into the coolant or externally. Particularly prone on vehicles built up to 2009.

Symptoms: Oil loss warning, oil spots under the left side of the vehicle, oil streaks visible on the belt tensioner

800–2,500 € from 120,000 km
!! Swirl Flap Linkage Breaks β€” Plastic Joint Fails

The plastic linkages of the swirl flaps in the OM642 intake manifold break. Aluminium repair kits are available and more durable. In the event of complete failure there is a risk of debris entering the engine.

Symptoms: Engine warning light, fault codes for intake flap/swirl flap, power loss particularly at low rpm

200–800 € from 100,000 km
!! Injector Seal Leaking β€” Soot Deposits and Diesel in Oil

Piezo injectors seal poorly from heat, diesel enters the engine oil. Oil loses lubrication properties, tar-like residue around injectors is the typical telltale sign.

Symptoms: Rough idle, increased fuel consumption, knocking noises, oil level rising due to diesel contamination, engine oil smells of diesel

300–900 € from 120,000 km
!! VTG Turbocharger Actuator Linkage Seized β€” Limp Mode

Variable turbine geometry actuator linkage seizes due to soot deposits. Engine enters limp mode. Fault codes P0404, P2598, P2385. If runner damage occurs, turbo costs from €1,300.

Symptoms: Sudden power loss on kickdown, limp mode, black smoke, engine oil in intercooler area

400–1,700 € from 180,000 km
!! Oil Pump Too Weak β€” Creeping Bearing Damage

The standard oil pump delivers insufficient pressure at high revs and temperatures. No warning in the cockpit. Connecting rod bearings wear unnoticed between 150,000–200,000 km, total engine failure looms.

Symptoms: Cold knocking at idle, metallic rattling during load changes, fine metal particles in oil filter, oil pressure drop only measurable late

2,500–8,000 € from 175,000 km
!! EGR System and Intake Manifold Coked Up

With frequent short-trip driving the EGR system on the OM642 becomes heavily coked. Soot deposits in the intake manifold significantly reduce airflow.

Symptoms: Power loss particularly under load, poor throttle response, soot clouds, elevated fuel consumption

300–1,000 € from 120,000 km
!! Glow Plugs Seized and Broken Off

Thin-walled glow plugs corrode in the cylinder head and break during removal. Broken heating element requires time-consuming drilling out. Replace all 6 plugs preventively.

Symptoms: Difficult cold starting, extended pre-glow time required, glow indicator flashes, white smoke at cold start in winter

400–1,100 € from 130,000 km

Vehicle Weaknesses 6

!! Suspension Airmatic air struts leaking

The air struts of the W221 wear over time. Between 200,000 and 300,000 km, all four struts typically need replacement.

2,300–5,500 € from 220,000 km
!! Suspension Pressure reservoir tank corroded (rear axle)

The Airmatic pressure reservoir tanks at the rear axle can corrode. Removal requires disassembly of the rear axle.

1,400–3,400 € from 180,000 km
!! Electronics Instrument cluster pixel faults and total failure

The instrument cluster develops pixel faults due to detached ribbon cables. In worst case, complete display failure.

200–600 € from 130,000 km
!! Electronics CAN bus faults and ESP failures

The W221 shows sporadic CAN bus communication faults leading to failures of various systems: ESP, headlight control, fog lights.

400–1,500 € from 150,000 km
!! Suspension Airmatic air spring bags leaking β€” vehicle sits lopsided

Air spring bags (usually rear) become leaky and lose pressure gradually. The vehicle then sits 3–4 cm lower on one side. Fault code 5285 (fill process too long) appears. Repair is only possible by replacement.

800–3,500 € from 120,000 km
! Electronics Comfort electronics faults: windows, mirrors, sunroof

The W221's extensive comfort electronics are fault-prone: electric windows, door mirrors and the optional panoramic sunroof show failures due to aged connectors and control units.

200–900 € from 100,000 km

Reports & Tests

nhtsa_complaints NHTSA Complaint Summary 2026-03
Below Average

233 owner complaints filed with NHTSA (2005–2013). Most reported: Electrical (63), Engine (41), Powertrain (35).